On April 22, 2025, the U.S. Department of Health and Human Services (HHS) and the Food and Drug Administration (FDA) announced that FDA is taking actions to phase out petroleum-based synthetic dyes from the U.S. food supply. The specific color additives that the agencies intend to eliminate are Blue No. 1, Blue No. 2, Green No. 3, Orange B, Citrus Red No. 2, Red No. 40, Yellow No. 5, and Yellow No. 6. These color additives are currently authorized for direct use in food pursuant to Title 21 Code of Federal Regulations (C.F.R.) Part 74. .....